New Mesothelioma Test Improves Diagnosis
Since introducing miRview™ meso in December 2008, Rosetta Genomics has already begun distributing the breakthrough test in Israel and Turkey.
miRview™ meso is a microRNA-based molecular diagnostic test that differentiates malignant pleural mesothelioma from other carcinomas in the lung. Malignant mesothelioma is a rare form of cancer that is almost exclusively caused by asbestos exposure. Those who are typically at risk of contracting the disease have either worked in the shipyard, construction, electrical, or automotive industry.
The test uses up-to-date molecular technologies for the processing and measuring of microRNAs. MicroRNAs, which are a newly-discovered family of genes in protein complexes, have been shown to be very specific to different types of tissues and tumors.
During the test, two separate scores are calculated to indicate the amount of mesothelioma and non-mesothelioma microRNAs in the sample. The scores are then analyzed to determine whether or not the sample is a mesothelioma or non-mesothelioma sample.
Although miRview™ meso is only being distributed to the public in Israel and Turkey, Rosetta Genomics has made the test commercially available to the United States through its Philadelphia-based CLIA-certified lab.
The test, which can only be ordered by a physician, simply requires a formalin-fixed, paraffin embedded (FFPE) tumor tissue sample to be shipped to Rosetta Genomics’ Philadelphia-based lab. Once the sample is received, results can be available within 10 business days.
This test is a critical breakthrough for diagnosing mesothelioma. Currently, there is no single marker that is entirely conclusive for either malignant mesothelioma or metastatic tumor, which often makes it difficult for physicians to make a complete diagnosis. However, Rosetta Genomics’ miRview™ meso test applies microRNA biomarkers and molecular technology to address this clinical need. High confidence cases have already shown 100 percent accuracy in determining the presence of mesothelioma.
Through the duration of 2009, Rosetta Genomics expects to conduct about 2,000 miRview™ meso tests in its laboratory in Philadelphia, Pennsylvania.
For more information on mesothelioma, please visit the Mesothelioma Cancer Center.
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