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	<title>Comments on: New Drug Prevents Radiation Damage</title>
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	<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/</link>
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	<pubDate>Fri, 19 Mar 2010 20:16:25 +0000</pubDate>
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		<title>By: Noreen</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-8756</link>
		<dc:creator>Noreen</dc:creator>
		<pubDate>Wed, 25 Jun 2008 03:32:56 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-8756</guid>
		<description>This is to Stine...

I was diagnosed with cancer last year.  I agree with you that if we found and solved the problem of the cause of the tumors, we would be much better off.  However, it seems as though everything causes cancer these days.  Those idiots who won't stop smoking, even though they KNOW it is a carcinogen, also pollute OUR air; we have no control over this.  I was always the outcast growing up in the 60's...I opted not to smoke, do drugs or drink.  I am glad to see that this is a changing trend.

I have friends living in Grand Blanc, MI.  Their water tested five times the maximum limit for arsenic.  They had to buy a filter for their house to the tune of  $1600.00.  They also have to change the liner periodically or the affected water can leach through the system.  My friends are constantly ill.  They tell me that the water tested fine going through this filter, but does it?  Is there something else in it that is making them ill?  The toxic dump there hurts people living near them, but the owners are making money off allowing Canada to continue to dump their toxic waste there, so who cares about those people who have cancer?  We have no control over that, either.   Too bad they don't realize that someday soon, it might be THEM, or someone they love, who gets cancer.  They will be wondering what caused their tumors.  People need to wake up and see the reality of this before the entire country gets terminally ill.</description>
		<content:encoded><![CDATA[<p>This is to Stine&#8230;</p>
<p>I was diagnosed with cancer last year.  I agree with you that if we found and solved the problem of the cause of the tumors, we would be much better off.  However, it seems as though everything causes cancer these days.  Those idiots who won&#8217;t stop smoking, even though they KNOW it is a carcinogen, also pollute OUR air; we have no control over this.  I was always the outcast growing up in the 60&#8217;s&#8230;I opted not to smoke, do drugs or drink.  I am glad to see that this is a changing trend.</p>
<p>I have friends living in Grand Blanc, MI.  Their water tested five times the maximum limit for arsenic.  They had to buy a filter for their house to the tune of  $1600.00.  They also have to change the liner periodically or the affected water can leach through the system.  My friends are constantly ill.  They tell me that the water tested fine going through this filter, but does it?  Is there something else in it that is making them ill?  The toxic dump there hurts people living near them, but the owners are making money off allowing Canada to continue to dump their toxic waste there, so who cares about those people who have cancer?  We have no control over that, either.   Too bad they don&#8217;t realize that someday soon, it might be THEM, or someone they love, who gets cancer.  They will be wondering what caused their tumors.  People need to wake up and see the reality of this before the entire country gets terminally ill.</p>
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		<title>By: A few points to clarify</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6608</link>
		<dc:creator>A few points to clarify</dc:creator>
		<pubDate>Sun, 13 Apr 2008 13:49:43 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6608</guid>
		<description>"Think About It" (18)

Taking only the information in the article above, your argument seems valid. However, with some background information on NF-KB you will soon realize that the drug is as unlikely to cause cancer.than a bacterial infection (notice the drug takes its active ingredient from a bacterium). A short-term activation of the NF-KB pathway occurs as a reaction to many different stimuli your cells are exposed to every day. The way I read the above information this is exactly what you would get -- short term activation prior to and during radiation therapy sessions

Regarding the hazard of the radiation therapy itself in presence of the drug:

Think about the skin cancer league's education program. They always tell you that severe sunburn leading to peeling skin before the age of 25 is at the origin of most melanomas -- even the ones people get at 80. This is because a single mutation is not enough to switch a normal cell to a cancer cell. It takes a combination of mutations (a large set of different combinations may lead to similar cancerous growths and symptoms but leaves the cancer/patient with differing outcomes of a given therapy -- see cancer sub-types). Depending on the radiation dosage and pre-existing mutations, it is likely that a new cancer will only arise at a much later date. When the choice is between dying of cancer at 60 and radiation therapy with this protection and an associated increase in the risk of having another cancer elsewhere in the body at 75-90 I think the choice from a medical perspective will be simple. In the end, considerations of religion, and personal beliefs will still affect the patient's own decision, but the doctors will be able to state the medical facts pretty clearly on that one.

Cheers,

A few points to clarify</description>
		<content:encoded><![CDATA[<p>&#8220;Think About It&#8221; (18)</p>
<p>Taking only the information in the article above, your argument seems valid. However, with some background information on NF-KB you will soon realize that the drug is as unlikely to cause cancer.than a bacterial infection (notice the drug takes its active ingredient from a bacterium). A short-term activation of the NF-KB pathway occurs as a reaction to many different stimuli your cells are exposed to every day. The way I read the above information this is exactly what you would get &#8212; short term activation prior to and during radiation therapy sessions</p>
<p>Regarding the hazard of the radiation therapy itself in presence of the drug:</p>
<p>Think about the skin cancer league&#8217;s education program. They always tell you that severe sunburn leading to peeling skin before the age of 25 is at the origin of most melanomas &#8212; even the ones people get at 80. This is because a single mutation is not enough to switch a normal cell to a cancer cell. It takes a combination of mutations (a large set of different combinations may lead to similar cancerous growths and symptoms but leaves the cancer/patient with differing outcomes of a given therapy &#8212; see cancer sub-types). Depending on the radiation dosage and pre-existing mutations, it is likely that a new cancer will only arise at a much later date. When the choice is between dying of cancer at 60 and radiation therapy with this protection and an associated increase in the risk of having another cancer elsewhere in the body at 75-90 I think the choice from a medical perspective will be simple. In the end, considerations of religion, and personal beliefs will still affect the patient&#8217;s own decision, but the doctors will be able to state the medical facts pretty clearly on that one.</p>
<p>Cheers,</p>
<p>A few points to clarify</p>
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		<title>By: Sunder</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6606</link>
		<dc:creator>Sunder</dc:creator>
		<pubDate>Sun, 13 Apr 2008 13:18:07 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6606</guid>
		<description>Two major points: (a) Because it would be catastrophic emergency the drug should be free -- meaning compnay makes no money (b) what is the point when a world conflgration erupts..no value to humanity, and loss of human life is the least important thing.

The utility in cancer treatment will be so much limited that company will never make profit because will be hounded by lawsuits. For example, 800 out of some 25 million who took COX2 inhibitor dies, causing several cox2 inhibitor makers to shelf ~60billion dollars in reserve to fight the lawsuit. 

Furthermore, take example of bone calcifier medicines, some are "attributed"  to cause tuberomandibular cancer. Guess hwat happens to the drug maker...pissing in the pants! 

Finally, if you count how many "shokcing" headlines have really turned into markatble medicines, you will be shcked--98% fail to make second headline story.</description>
		<content:encoded><![CDATA[<p>Two major points: (a) Because it would be catastrophic emergency the drug should be free &#8212; meaning compnay makes no money (b) what is the point when a world conflgration erupts..no value to humanity, and loss of human life is the least important thing.</p>
<p>The utility in cancer treatment will be so much limited that company will never make profit because will be hounded by lawsuits. For example, 800 out of some 25 million who took COX2 inhibitor dies, causing several cox2 inhibitor makers to shelf ~60billion dollars in reserve to fight the lawsuit. </p>
<p>Furthermore, take example of bone calcifier medicines, some are &#8220;attributed&#8221;  to cause tuberomandibular cancer. Guess hwat happens to the drug maker&#8230;pissing in the pants! </p>
<p>Finally, if you count how many &#8220;shokcing&#8221; headlines have really turned into markatble medicines, you will be shcked&#8211;98% fail to make second headline story.</p>
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		<title>By: Norman A. Solow</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6531</link>
		<dc:creator>Norman A. Solow</dc:creator>
		<pubDate>Sat, 12 Apr 2008 20:10:35 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6531</guid>
		<description>Wow! What a great advancement. Especially for Cancer patients. My late Mother had Breast Cancer with bone issues that were treated with radiation &amp; bone enhancement drugs. Her last radiation treatment ruined her life since she stopped eating.

Their were other issues but had she not had the radiation side effects her quality of life might have been better. 

Keep the research going.

Norman</description>
		<content:encoded><![CDATA[<p>Wow! What a great advancement. Especially for Cancer patients. My late Mother had Breast Cancer with bone issues that were treated with radiation &amp; bone enhancement drugs. Her last radiation treatment ruined her life since she stopped eating.</p>
<p>Their were other issues but had she not had the radiation side effects her quality of life might have been better. </p>
<p>Keep the research going.</p>
<p>Norman</p>
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		<title>By: bert</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6517</link>
		<dc:creator>bert</dc:creator>
		<pubDate>Sat, 12 Apr 2008 16:05:03 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6517</guid>
		<description>"Think About It" (18) has a point -- quote "Let’s see… they find a drug which makes the entire body behave as if it is cancerous (prevent cell suicide). What could possibly go wrong?"

Isn't that exactly what big Pharma is looking for?  Modern notions of medical practice and Profit, by redistribution of wealth, which in turn can be stimulated by redistribution of health, are not unrelated.  After all, none of us wants a collapse of Wall Street's investment houses.  Let's all hope and prey, that Gudkov gets his American Dream fulfilled, and becomes a billionaire, and that our notions of Wall St. Profits, by redistribution of wealth, including those of big Pharma, by redistribution of symptoms while amplifying underlying medical causes, so as to cause a redistribution of health, can be preserved as the lawful perpetuity that it must, by universal proclamation, be.</description>
		<content:encoded><![CDATA[<p>&#8220;Think About It&#8221; (18) has a point &#8212; quote &#8220;Let’s see… they find a drug which makes the entire body behave as if it is cancerous (prevent cell suicide). What could possibly go wrong?&#8221;</p>
<p>Isn&#8217;t that exactly what big Pharma is looking for?  Modern notions of medical practice and Profit, by redistribution of wealth, which in turn can be stimulated by redistribution of health, are not unrelated.  After all, none of us wants a collapse of Wall Street&#8217;s investment houses.  Let&#8217;s all hope and prey, that Gudkov gets his American Dream fulfilled, and becomes a billionaire, and that our notions of Wall St. Profits, by redistribution of wealth, including those of big Pharma, by redistribution of symptoms while amplifying underlying medical causes, so as to cause a redistribution of health, can be preserved as the lawful perpetuity that it must, by universal proclamation, be.</p>
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		<title>By: didthat1x</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6473</link>
		<dc:creator>didthat1x</dc:creator>
		<pubDate>Sat, 12 Apr 2008 07:09:43 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6473</guid>
		<description>The greatest amount of radiation exposure from a nuclear event doesn't come from the initial blast.  Yes there is tremendous damage to those immediately outside of the blast radius/death zone from the high energy ionizing radiation, including neutron radiation.  Some exposure of concern comes from metal objects that would be activated by the neutron radiation, however the contamination(basically radioactive dust particles) that is inhaled or allowed to sit on your skin gives the chronic dose.  The greatest exposure would come in the form of Alpha and Beta radiation from the contamination.  An Alpha particle is a Helium atom without its electrons and Beta is a higher enrgy particle.  Alpha radiation is not harmful and not penetrating (stopped by the skin) unless it gets inside fo your body and GI tract or lungs where there is no protection and serious damage can occur.  Beta radiation penetrates the first few layers of skin, but not clothing, so your external exposure may look like a sunburn but with greater cellular damage.  If the contaminated particles are Beta emitters then your insides can really get a dose.
     OK, I'm done now. :-)</description>
		<content:encoded><![CDATA[<p>The greatest amount of radiation exposure from a nuclear event doesn&#8217;t come from the initial blast.  Yes there is tremendous damage to those immediately outside of the blast radius/death zone from the high energy ionizing radiation, including neutron radiation.  Some exposure of concern comes from metal objects that would be activated by the neutron radiation, however the contamination(basically radioactive dust particles) that is inhaled or allowed to sit on your skin gives the chronic dose.  The greatest exposure would come in the form of Alpha and Beta radiation from the contamination.  An Alpha particle is a Helium atom without its electrons and Beta is a higher enrgy particle.  Alpha radiation is not harmful and not penetrating (stopped by the skin) unless it gets inside fo your body and GI tract or lungs where there is no protection and serious damage can occur.  Beta radiation penetrates the first few layers of skin, but not clothing, so your external exposure may look like a sunburn but with greater cellular damage.  If the contaminated particles are Beta emitters then your insides can really get a dose.<br />
     OK, I&#8217;m done now. <img src='http://medheadlines.com/wp-includes/images/smilies/icon_smile.gif' alt=':-)' class='wp-smiley' /> </p>
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		<title>By: links for 2008-04-12 &#171; mghicks</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6467</link>
		<dc:creator>links for 2008-04-12 &#171; mghicks</dc:creator>
		<pubDate>Sat, 12 Apr 2008 06:34:28 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6467</guid>
		<description>[...] MedHeadlines» Cancer Drugs Medical Research Prevention » New Drug Prevents Radiation Damage (tags: readthis medicine)     Posted in Links. [...]</description>
		<content:encoded><![CDATA[<p>[...] MedHeadlines» Cancer Drugs Medical Research Prevention » New Drug Prevents Radiation Damage (tags: readthis medicine)     Posted in Links. [...]</p>
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		<title>By: joe</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6463</link>
		<dc:creator>joe</dc:creator>
		<pubDate>Sat, 12 Apr 2008 05:43:11 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6463</guid>
		<description>stine, you drink too much kool-aid.  get an education.</description>
		<content:encoded><![CDATA[<p>stine, you drink too much kool-aid.  get an education.</p>
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		<title>By: Gina</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6445</link>
		<dc:creator>Gina</dc:creator>
		<pubDate>Sat, 12 Apr 2008 01:11:51 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6445</guid>
		<description>Stine..I admire your passion; however , your facts regarding cancer treatment and survival rates are way off.</description>
		<content:encoded><![CDATA[<p>Stine..I admire your passion; however , your facts regarding cancer treatment and survival rates are way off.</p>
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		<title>By: Think About It</title>
		<link>http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/comment-page-1/#comment-6443</link>
		<dc:creator>Think About It</dc:creator>
		<pubDate>Sat, 12 Apr 2008 00:48:31 +0000</pubDate>
		<guid isPermaLink="false">http://medheadlines.com/2008/04/11/new-drug-prevents-radiation-damage/#comment-6443</guid>
		<description>Let's see... they find a drug which makes the entire body behave as if it is cancerous (prevent cell suicide).  What could possibly go wrong?  Interesting that the article makes no mention of a long-term study to see whether the drug in fact causes cancer.  The "remarkable result" if legitimate is perhaps academically interesting but may be of no practical value in cancer treatment if it merely triggers massive cancer throughout the body (which seems quite possible).  If legitimate, however, it could enable a human being to commit slow-motion suicide but able to perform some tasks in a high-radiation environment for a longer time than if untreated.  Potentially some military applications here.  It is pretty creepy they are torturing and killing primates for this purpose.  Oh yeah, it's not torture if it's not a human, right?</description>
		<content:encoded><![CDATA[<p>Let&#8217;s see&#8230; they find a drug which makes the entire body behave as if it is cancerous (prevent cell suicide).  What could possibly go wrong?  Interesting that the article makes no mention of a long-term study to see whether the drug in fact causes cancer.  The &#8220;remarkable result&#8221; if legitimate is perhaps academically interesting but may be of no practical value in cancer treatment if it merely triggers massive cancer throughout the body (which seems quite possible).  If legitimate, however, it could enable a human being to commit slow-motion suicide but able to perform some tasks in a high-radiation environment for a longer time than if untreated.  Potentially some military applications here.  It is pretty creepy they are torturing and killing primates for this purpose.  Oh yeah, it&#8217;s not torture if it&#8217;s not a human, right?</p>
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